ESP32-S3-DevKitC-1

Fig. 1. ESP32-S3-DevKitC-1, 2x22 2.54 mm. Hover or tap a signal to light up every pin that carries it.

• GPIO35, GPIO36 and GPIO37 are not available on modules with octal SPI PSRAM or flash, which covers the N8R8 and N16R8 WROOM-1 variants and every WROOM-2. On those boards the three pins are wired to the memory and using them crashes the chip. Check the module label before you design them in.
• The RGB LED moved between revisions: GPIO38 on v1.1, GPIO48 on v1.0. Example code that blinks nothing is usually this and not a broken LED.
• GPIO19 and GPIO20 are the native USB data lines. Use them as GPIOs and the ESP32-S3 USB port stops working, which also costs you USB-serial-JTAG debugging.
• Strapping pins are GPIO0 (BOOT), GPIO3, GPIO45 and GPIO46. They are sampled at reset, so what you hang on them decides how the chip boots. GPIO0 is the one wired to the BOOT button.
• ADC2 channels are unusable while Wi-Fi is running. That takes out GPIO11 through GPIO20 for analog, so put anything you need to measure on ADC1, which is GPIO1 to GPIO10.
• There are two USB ports. The one marked UART goes through a CP2102 bridge and always works for flashing. The one marked USB is the chip's own, and it is the one that disappears if you repurpose GPIO19 and GPIO20.
• The three ways to power the board are mutually exclusive: the USB ports, the 5V and G pins, or the 3V3 and G pins. Feeding two at once is how regulators die.
• Pin 1 of each header is at the antenna end, which is the top of this diagram, with both USB connectors at the bottom.

Table 1. Pin assignments.